Impaired Spatial Memory and Enhanced Habit Memory in a Rat Model of Post-traumatic Stress Disorder

摘要

FIGURE 1. Influence of single-prolonged stress (SPS) on acquisition and extinction of hippocampus-dependent place learning in the plus-maze. SPS rats displayed a lower proportion of correct turning responses during acquisition (Days 1–12), relative to control rats, indicating an impairment of place learning. SPS rats were also slower to reduce the proportion of correct turning responses during extinction training (Days 13–17), indicating an impairment in extinction of place learning.