EVALUATION OF THE PREVALNENCE AND PATTERN OF CORONARY ARTERY DISEASE IN PATIENTS WITH END STAFGE RENAL DISEASE BY SELECTIVE CORONARY ARTERIOGRAPHY

摘要

Background & Aims: Mortality risk of cardiovascular disease in patients with End Stage Renal Disease (ESRD) is more than general population. Hence, if it isnot regarded, it will result in reduced survival and death in ESRD patients especially who are renal transplant candidates. Aim of the present study was the evaluation of the frequency and pattern of CAD in ESRD patients with candidates to kidney transplantion and their relation with duration of dialysis regarding remarkable prevalence of CAD in this group of patients. Materials & Methods: In this study, we evaluated 56 patients (24 females and 32 males) with renal transplantation who underwent coronary angiography for assessment of CAD prevalence, pattern of vessels involvement and need for revascularization. We also assessed the association between the underlying causes of ESRD (such as diabetes mellitus and hypertension and so.), duration of dialysis, and CAD. Results: The prevalence of CAD in ESRD Patients were 60.7% (34) that 82.3% (28 patients) of them were candidate for revascularization. There was no significant correlation between number of diseased vessels, underlying disease of ESRD and duration of dialysis. No statistically significant association was observed between the need for revascularization and age of patients, underlying disease or duration of dialysis. Conclusion: In regard to high prevalence of coronary artery disease in renal transplant candidates, particularly in patients with cardiovascular risk factors, it seems that angiography (instead of non-invasive testing) and effective treatment of CAD before transplantation is really necessary.