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Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan

机译:全结肠镜检查在日本大肠癌筛查中的成本效益

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Introduction. In Japan, the cost-effectiveness of total colonoscopy (TCS) for primary screening of colorectal cancer (CRC) is unclear. We compared the cost of identifying a patient with CRC using two primary screening strategies: TCS (strategy 1) and the immunochemical fecal test (FIT) (strategy 2).Materials and Methods. We retrospectively analyzed the TCS screening database at our institution from February 2004 to August 2010 (strategy 1,n=15,348) and the Japanese nationwide survey of CRC screening in 2008 (strategy 2,n=5,267,443).Results. 112 and 6,838 CRC cases were detected in strategies 1 and 2, costing 2,124,000 JPY and 1,629,000 JPY, respectively. The rate of earlier-stage CRC was higher in strategy 1.Conclusions. The cost was higher using TCS as a primary screening procedure. However, the difference was not excessive, and considering the increased rate of detecting earlier CRC, the use of TCS as a primary screening tool may be cost-effective.
机译:介绍。在日本,用于结肠直肠癌(CRC)初筛的全结肠镜检查(TCS)的成本效益尚不清楚。我们比较了使用两种主要的筛查策略(TCS(策略1)和免疫化学粪便测试(FIT)(策略2))识别CRC患者的成本。材料和方法。我们回顾性分析了我院2004年2月至2010年8月的TCS筛查数据库(策略1,n = 15,348)和日本全国CRC筛查2008年的全国性调查(策略2,n = 5,267,443)。结果。在策略1和策略2中检测到112例和6,838例CRC,分别花费2,124,000日元和1,629,000日元。在策略1中,早期CRC的发生率较高。使用TCS作为主要筛查程序的成本较高。但是,差异并不算太大,考虑到早期CRC检出率的提高,使用TCS作为主要筛查工具可能具有成本效益。

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