Evaluation of Antenatal Maternal Serum Biomarkers in Pregnancies Over 41 Weeks

摘要

OBJECTIVE: To examine association between maternal antenatal serum biomarkers and post-term?pregnancies. STUDY DESIGN: Singleton pregnant women (n=186) managed at the Zekai Tahir Burak Women’s?Health, Education and Research Hospital in Turkey from July 2010 to December 2010 were analyzed?retrospectively. Maternal serum levels of PAPP-A, free β-hCG, AFP, HCG and unconjugated E3 were?noted routinely in antenatal screening programs. We compared these biomarkers in pregnancies between?37 and 41 gestational weeks (n=73) and ≥41 (n=113) gestational weeks. RESULTS: There was no statistically significant difference in maternal PAPP-A, free beta-hCG, AFP,?total hCG and unconjugated E3 levels between the two groups. Although birth weights were higher in?pregnant women ≥41 weeks, this difference was not considered significant (p=0.19). There were no SGA?babies in the group of post-term pregnancies. CONCLUSION: There were no statistically significant differences in maternal serum markers for pregnant?women having their period of ≥41 gestational week.