目的：分析妊娠期糖尿病孕妇产前血清网膜素1表达与围生儿结局关系。方法：选取2013年1月-2014年1月在笔者所在医院进行剖宫产或自然分娩孕37~41周孕妇120例，依据葡萄糖耐量试验结果分为对照组(血糖正常孕妇)和观察组（妊娠期糖尿病），抽取两组患者静脉血5 ml，检测血清网膜素1水平并统计新生儿结局及并发症情况。结果：观察组妊娠期糖尿病孕妇产前血清网膜素1水平与新生儿体重、1 min及5 min Apgar评分明显低于对照组，差异有统计学意义(P<0.05)；观察组妊娠感染、新生儿窒息情况均高于对照组，但差异无统计学意义(P>0.05)；观察组妊娠高血压疾病、巨大儿情况明显高于对照组，差异有统计学意义(P<0.05)。结论：妊娠期糖尿病孕妇血清网膜素1低于健康产妇，其围生儿结局较差，可能与血清网膜素1较低有关。%Objective:To analyze the gestational diabetes prenatal serum retinal pigment 1 expression of the relationship between perinatal outcome. Method:120 cases of cesarean section or natural childbirth pregnant 37-41 weeks pregnant from January 2013 to January 2014 in our hospital were selected, according to the glucose tolerance test they were divided into control group(the glucose was normal) and observation group(diabetes in pregnancy),two groups of patients with venous blood in 5 ml,the serum level of omentin 1 were detected and neonatal outcomes and complications were statisticsed.Result:The group of pregnant women with gestational diabetes film prenatal serum hormone levels and a birth weight,one minute and five minutes Apgar score were significantly lower than the control group,the differences were statistically significant(P<0.05);observation group pregnant infection,asphyxia cases were higher,but the difference was no statistically significant(P>0.05);observation group pregnancy-induced hypertension,a huge children cases significantly higher,the differences were statistically significant(P<0.05).Conclusion:Gestational diabetes mellitus pregnant women serum omentin 1 is lower than the healthy maternal,perinatal outcomes may be poor,it may be related with serum omentin 1 lower.
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