Validation of a Method for Analysis of Avermectins Residues in Bovine Milk by HPLC-Fluorescence Detector

摘要

The presence of veterinary drug residues in bovine milk has raised the need to adapt their detection methodologies in milk for human consumption. The avermectins, antiparasitic class have been detected by liquid chromatography with fluorescence detection after derivatization reaction. The method validated in this work is fast and accurate for the determination of these residues in bovine milk according with limits establishment by Codex Alimentarius . The limit of quantitation (LOQ) for Abamectin, Doramectin and Ivermectin is 5 μg L~(-1) with a great recovery associated with a low coefficient of variation.