Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan

Yoshihiko Sakaguchi; Koji Hosomi; Jumpei Uchiyama; Yoshitoshi Ogura; Kaoru Umeda; Masakiyo Sakaguchi

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Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan

机译：从日本一名肉毒杆菌感染患者中分离到的B型肉毒梭菌Osaka05基因组序列草案。

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Clostridium botulinum strain Osaka05, which has been isolated from an infant patient with botulism in Japan, is the first strain producing botulinum neurotoxin subtype B6. Here, we report the draft genome sequence of C.?botulinum Osaka05.

机译：从日本一名患有肉毒中毒的婴儿患者中分离出的肉毒梭菌菌株Osaka05是第一批产生肉毒杆菌神经毒素B6亚型的菌株。在这里，我们报告了肉毒梭菌 Osaka05的基因组序列草案。 展开▼

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《Genome Announcements》 |2014年第1期|共2页

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Yoshihiko Sakaguchi; Koji Hosomi; Jumpei Uchiyama; Yoshitoshi Ogura; Kaoru Umeda; Masakiyo Sakaguchi;
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中图分类基因工程（遗传工程）;

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专利

1. Antimicrobial Susceptibility of 260 Clostridium botulinum Type A, B, Ba, and Bf Strains and a Neurotoxigenic Clostridium baratii Type F Strain Isolated from California Infant Botulism Patients [J] . Barash Jason R. ocr issue, Castles Joe B. III, Arnon Stephen S. Antimicrobial agents and chemotherapy. . 2018,第12期

机译：260型肉毒杆菌型A，B，Ba和BF菌株的抗菌易患性和来自加州婴儿肉类主义患者分离的神经毒素梭菌Baratii型F株

2. Complete nucleotide sequence of a plasmid containing the botulinum neurotoxin gene in Clostridium botulinum type B strain 111 isolated from an infant patient in Japan [J] . Hosomi Koji, Sakaguchi Yoshihiko, Kohda Tomoko, Molecular genetics and genomics: MGG . 2014,第6期

机译：分离自日本一名婴儿患者的B型肉毒梭菌菌株中含有肉毒杆菌神经毒素基因的质粒的完整核苷酸序列

3. Dual Toxin-Producing Strain of Clostridium botulinum Type Bf Isolated from a California Patient with Infant Botulism [J] . Jason R. Barash, Stephen S. Arnon Journal of Clinical Microbiology . 2004,第4期

机译：从产妇肉毒杆菌中毒的加利福尼亚患者中分离出双产毒素的肉毒梭菌Bf型菌株。

4. Mass Spectrometric Forensic Analysis of Botulinum Neurotoxin Type A Isolated from Infant Formula and Patient Stool [C] . Suzanne R. Kalb, Jakub Baudys, John R. Barr ASMS Conference on Mass Spectrometry and Allied Topics . 2014

机译：肉毒杆菌神经毒素型分离婴幼儿配方和患者粪便的质谱法官分析

5. Toxicity of Clostridium botulinum type E neurotoxin to Great Lakes fish: Implications to avian botulism. [D] . Yule, Adam Murray. 2005

机译：E型肉毒梭菌神经毒素对五大湖鱼类的毒性：对禽肉毒杆菌中毒的影响。

6. Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05 Isolated from an Infant Patient with Botulism in Japan [O] . Yoshihiko Sakaguchi, Koji Hosomi, Jumpei Uchiyama, 2014

机译：从日本婴儿肉毒杆菌中分离出的B型肉毒梭菌Osaka05基因组序列草案。

7. Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan [O] . Yoshihiko Sakaguchi, Koji Hosomi, Jumpei Uchiyama, 2014

机译：梭菌肉毒杆菌菌菌株大阪菌株的基因组序列草案，与日本有肉毒杆菌中的婴儿患者分离出来

1. C型肉毒梭菌的分离及鉴定 [J] . 吴伟 ,刘志龙 ,张晶 . 新疆农业科学 . 2013,第004期

2. 1株与生孢梭菌混同生长的E型肉毒梭菌的分离 [J] . 赵文彬 . 江苏预防医学 . 1997,第003期

3. 一株山羊源2型溶血性曼氏杆菌的分离鉴定及全基因组序列分析 [J] . 芦彪 ,张保海 ,罗梓丹 . 云南农业大学学报 . 2021,第004期

4. 云南省蓝舌病病毒血清7型毒株的分离与基因组序列分析 [J] . 李占鸿 ,杨恒 ,宋子昂 . 畜牧兽医学报 . 2021,第005期

5. 一株G6P5型牛轮状病毒的分离鉴定与全基因组序列分析 [J] . 曹存 ,于德斌 ,徐晓静 . 中国预防兽医学报 . 2021,第009期

6. C型肉毒梭菌的分离及肉毒毒素的制备、鉴定 [C] . 李剑 ,刘志龙 ,阳林 . 纪念中国微生物学会成立六十周年大会暨2012年中国微生物学会学术年会 . 2012

7. 新疆豆制品生产环境中肉毒梭菌分离鉴定及其控制技术研究 [A] . 刘凯 . 2012

1. 使用来自肉毒梭菌的血清型的重链的基于单价或多价肉毒杆菌神经毒素的疫苗 [P] . 中国专利： CN105209066A . 2015-12-30

2. 肉毒梭菌血清型A亚型中质粒编码的神经毒素基因 [P] . 中国专利： CN101848930A . 2010-09-29

3. Novel DNA sequences of the botulinum neurotoxin complex of Clostridium botulinum type A-Hall (Allergan) strain for production of therapeutics [P] . 外国专利： US2005169942A1 . 2005-08-04

机译：用于生产疗法的肉毒梭菌A型霍尔（Allergan）菌株肉毒杆菌神经毒素复合物的新DNA序列

4. Plant protein isolated from other plant proteins antifungal composition sequence of isolated DNA sequence expressive recombinant DNA sequence in plants cloning vehicle or bacterial strain vector bacterial strain of the genus agrobacterium plant cell genome or plant material of the same process for the reproduction of a variety of plants that have reduced susceptibility to fungi and process to inhibit growth and/or germination of a fungus [P] . 外国专利： BR9407352A . 1997-09-16

机译：从其他植物蛋白中分离得到的植物蛋白抗真菌成分序列分离的DNA序列表达植物中的重组DNA序列农杆菌属植物细胞基因组或植物材料的克隆载体或细菌菌株载体细菌菌株可用于多种植物的繁殖降低了对真菌的敏感性和抑制真菌生长和/或发芽的过程

5. Fusion protein Fusion protein The soluble composition of the host cell material Process to generate a neutralizing anti-toxin directed against Clostridium botulinum toxin type A antibody to purify a recombinant fusion protein derived from a Clostridium botulinum toxin type A process to generate an antitoxin neutralizing directed against clostridium difficile toxin type b antibody treatment process process to generate a neutralizing antitoxin directed against clostridium difficile type a toxin composition process to vaccinate an individual to produce neutralizing antitoxin directed against clostridium difficile toxin processing the detection of clostridium antigens difficile in an ample process of purification of toxins from clostridium difficile from a culture and process of generation of a solid dosage form of a bird antitoxin directed against a protein of clostridial toxin [P] . 外国专利： BR9509903A . 1997-11-25

机译：融合蛋白融合蛋白宿主细胞材料的可溶性组成物产生针对A型肉毒梭菌毒素的中和抗毒素的过程纯化源自A型肉毒杆菌毒素的重组融合蛋白的抗体产生针对人肉毒杆菌的抗毒素的过程B型艰难梭菌毒素抗体处理工艺过程，产生针对A艰难梭菌毒素的中和抗毒素组合物，对个体进行疫苗接种，以生产针对艰难梭菌毒素的中和抗毒素，在充足的纯化纯化过程中检测艰难梭菌抗原来源于梭状芽胞杆菌毒素蛋白的鸟抗毒素固体剂型的培养物和固体剂型产生过程中的艰难梭菌毒素

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Draft Genome Sequence of Clostridium botulinum Type B Strain Osaka05, Isolated from an Infant Patient with Botulism in Japan

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