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Whole-Genome Sequencing of the Nonproteolytic Bacillus anthracis V770-NP1-R Strain Reveals Multiple Mutations in Peptidase Loci

机译:非蛋白水解炭疽杆菌V770-NP1-R株的全基因组测序揭示了肽酶基因座中的多个突变。

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摘要

We report the draft whole-genome sequence of the nonproteolytic Bacillus anthracis V770-NP1-R strain. Compared to those of other B.?anthracis strains, the genome exhibits unique mutations in multiple targets potentially affecting proteolytic functions. One of these mutations is a deletion that disrupts the NprR quorum-sensing regulator of the NprA protease.
机译:我们报告了非蛋白水解炭疽芽孢杆菌V770-NP1-R株的全基因组序列草案。与其他炭疽杆菌菌株相比,该基因组在多个靶标中均表现出独特的突变,可能会影响蛋白水解功能。这些突变之一是破坏NprA蛋白酶的NprR群体感应调节剂的缺失。

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