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Complete Genome Sequences of Two Multidrug-Resistant Mycobacterium tuberculosis Strains Isolated in Guiyang, China

机译:贵阳分离的两个耐多药结核分枝杆菌菌株的完整基因组序列

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We identified the genome sequences of two Mycobacterium tuberculosis isolates. They were resistant to rifampin and isoniazid, as determined by the agar proportion method, but were susceptible to isoniazid, as determined by the DNA array method. The genome sequences showed that a katG deletion led to the false diagnosis of isoniazid resistance by DNA array.
机译:我们确定了两个结核分枝杆菌分离株的基因组序列。如通过琼脂比例法测定,它们对利福平和异烟肼具有抗性,但如通过DNA阵列方法测定,它们对异烟肼敏感。基因组序列显示,katG缺失导致通过DNA阵列错误诊断异烟肼抗性。

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