Disability in Inflammatory Bowel Disease: Translation to Portuguese and Validation of the “Inflammatory Bowel Disease – Disability Score”

摘要

Background: Inflammatory bowel disease (IBD) has a physical, psychological and social impact,often compromising the patient抯 ability to perform daily activities. Recently a new measurementfor disability in IBD was developed. The Inflammatory Bowel Disease-Disability Score(IBD-DS) comprises the following domains: mobility, self-care, major daily life activities,gastrointestinal-related problems, mental health and interaction with the environment. Theaim of our study was to translate to Portuguese and to validate the IBD-DS.Methods: Eighty-five patients, 55 with Crohn抯 disease (CD) and 30 with ulcerative colitis (UC),completed the Portuguese version of the IBD-DS and the short inflammatory bowel diseasequestionnaire (SIBDQ-10 questions). Disease activity was assessed using the Harvey---Bradshaw(HB) for CD and partial Mayo score (pMayo) for UC. Pearson抯 correlation coefficient was used toassess the correlation between the IBD-DS and SIBDQ. The Student抯 t-test was used to comparethe mean of IBD-DS between active and inactive disease. Statistical analysis was performed withSPSS 21.0 and the statistical level of significance (? was established at 5%.Results: In our study, a significant negative correlation between the IBD-DS and the SIBDQ wasobserved (r =-0.858, p < 0.001 for CD and r =-0.933, p < 0.001 for UC). There was a statisticallysignificant difference of the mean of IBD-DS between inactive vs. active disease (93.78 vs.117.57, p = 0.016 for CD and 78.96 vs. 137.14, p < 0.001 for UC).Conclusion: The Portuguese version of the inflammatory bowel disease-disability score has astrong correlation with patients?quality of life and clinical disease activity and was shown tobe a valid tool to measure disability in patients with inflammatory bowel disease.