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Diallel Cross Analysis of Body Weight in Subspecies of Mice

机译:小鼠亚种体重的Diallel交叉分析

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A complete 4 × 4 diallel cross of CF#1 (C), C57BL/6NCrj (B) C3H/HeNCrj (H) and Yonakuni wild mice (Y, Mus musculus molossinus yonakuni) has been conducted to estimate the effects of sex, degree of heterosis, general combining ability (gca), specific combining ability (sca), maternal ability, and reciprocal cross on body weight at 1(Wk1), 3 (Wk3), 6 (Wk6) and 10 (Wk10) weeks of age. A least squares analysis was performed on 828 mice and all sources of variation showed significant effects (P0.05). Males were heavier than females (PH>B>Y. Crossing between C and H had greater sca than other combinations at all ages studied, whereas B ¤ Y had the smallest. Mean body weight of the offspring from two-line reciprocal cross differed according to their dam. A relatively large proportion of additive genetic effects in contributing to the variation in offspring body weight was indicated.
机译:已进行了CF#1(C),C57BL / 6NCrj(B)C3H / HeNCrj(H)和Yonakuni野生小鼠(Y,Mus musculus molossinus yonakuni)完整的4×4拨号杂交,以评估性别,程度的影响。年龄,1周(Wk1),3周(Wk3),6周(Wk6)和10周(Wk10)时的杂种优势,一般结合能力(gca),特异性结合能力(sca),母体能力和体重的倒数。对828只小鼠进行了最小二乘分析,所有变异来源均显示出显着效果(P0.05)。雄性比雌性重(PH> B> Y。在所有研究的年龄段,C和H的交配比其他组合的sca更大,而B¤Y的交配比最小。两系互交的后代的平均体重根据结果表明,在其后代体重变化中,相对较大比例的附加遗传效应。

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