3-ALKOXY-1,5-DIARYL-4,5-DIHYDROXYIMIDAZOLIDIN-2-ONES AND 3-ALKOXY-1-ALKYL-5-ARYL-4,5-DIHYDROXYIMIDAZOLIDIN-2-ONES: SYNTHESIS AND STRUCTURE

摘要

It has been found that 4-nitrophenylglyoxal reacts with N -alkoxy- N’ -arylureas and N -alkoxy- N’ -alkylureas in acetic acid medium with the selective formation of the diastereomers of the 3-alkoxy-1,5-diaryl-4,5-dihydroxyimidazolidin-2-ones and 3-alkoxy-1-alkyl-5-aryl-4,5-dihydroxyimidazolidin-2-ones with sic -orientation of OH-groups. The X-ray structural analysis of 3-propyloxy-4 S ,5 S -dihydroxy-1-methyl-5-(4-nitrophenyl)imidazolidin-2-one and of 3- n -butyloxy-4 S ,5 S -dihydroxy-1-(4-methylphenyl)-5-(4-nitrophenyl)imidazolidin-2-one has demonstrated the structural parameters of these compounds.