Dear Editor, Fowl adenovirus (FAdV) belongs to the genus Aviadenoviru s and has been clustered into five species (A–E) with 12 serotypes. 1 Although this virus has spread globally, FAdV infection typically causes only subclinical symptoms, and severe FAdV infection is associated with inclusion body hepatitis (IBH), hydropericardium syndrome (HPS) and gizzard erosion and ulceration. 1 , 2 , 3 , 4 , 5 , 6 , 7 , 8 Notably, severe FAdV cases with IBH and HPS in chicken flocks have been observed in China since 2013. 9 These outbreaks typically occurred in 3–5-week-old broiler flocks, as well as in 10–20-week-old layer flocks. In contrast to mild disease caused by previous FAdV outbreaks, the outbreaks of FAdV in 2015 in China caused a huge economic loss in the poultry industry.
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