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Impact of a ‘stent for life’ initiative on post‐ST elevation myocardial infarction heart failure: a 15?year heart failure clinic experience

机译:“终身支持”计划对ST后抬高型心肌梗塞心力衰竭的影响:15年心衰诊所经验

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Aims Multidisciplinary heart failure (HF) clinics are a cornerstone of contemporary HF management. The stent‐for‐life (SFL) initiative improves mortality after ST elevation myocardial infarction (STEMI), but its impact in post‐STEMI HF is not well characterized. Here we assessed the impact of SFL among patients referred to a multidisciplinary HF clinic over a 15?year time period. Methods and results Between 2001 and 2015, 1921 patients were admitted to our HF clinic. In 2009, Catalonia established the Codi IAM network, a regional STEMI network that prioritizes primary percutaneous coronary intervention in STEMI. Patients admitted during the study period were divided into two groups based on admission date: pre‐SFL (2001–June 2009; n ?=?1031) and post‐SFL (July 2009–2015; n ?=?890). Compared with those in the pre‐SFL group, patients admitted in the post‐SFL period had better New York Heart Association (NYHA) functional class (22.1 vs. 38.7 NYHA classes III–IV; P ??0.001) and higher left ventricular ejection fraction (LVEF) (36.1?±?19.6 vs. 32.6?±?13.4; P ??0.001). Among STEMI survivors, 101 (6.7%) pre‐SFL patients and 40 (2%) post‐SFL patients ( P ??0.001) fulfilled the criteria for HF clinic referral (Killip–Kimball class?≥?2 during index admission and/or LVEF of 40%). Furthermore, among patients admitted to the HF clinic, post‐STEMI HF with reduced ejection fraction patients comprised 8.9% of the pre‐SFL group and only 4.2% of the post‐SFL group ( P ??0.001). Conclusions Among patients treated at our multidisciplinary HF clinic, the adoption of an SFL network has decreased the prevalence of post‐STEMI HF with reduced ejection fraction.
机译:目的多学科心力衰竭(HF)诊所是当代HF管理的基石。终身支架(SFL)计划可改善ST抬高型心肌梗死(STEMI)后的死亡率,但其对STEMI HF后的影响尚不明确。在这里,我们评估了在15年的时间内转诊至多学科HF诊所的患者中SFL的影响。方法和结果2001年至2015年,我们的HF诊所收治了1921例患者。 2009年,加泰罗尼亚建立了Codi IAM网络,这是一个区域性STEMI网络,该网络优先考虑STEMI的主要经皮冠状动脉介入治疗。在研究期间入院的患者根据入院日期分为两组:SFL之前(2001年– 2009年6月; n == 1031)和SFL之后(2009年7月–2015年; n == 890)。与SFL之前的组相比,SFL之后入院的患者具有更好的纽约心脏协会(NYHA)功能等级(32.1 – 38.7级NYHA III–IV; P <0.001)和更高的左心室射血分数(LVEF)(36.1±±19.6比32.6±±13.4; P << 0.001)。在STEMI幸存者中,有101名(6.7%)SFL前患者和40名(2%)SFL后患者(P 0.001)符合HF诊所转诊的标准(Killip-Kimball类≥2)。 /或LVEF <40%)。此外,在HF诊所入院的患者中,STEMI后HF射血分数降低的患者占SFL前组的8.9%,而仅占SFL后组的4.2%(P <0.001)。结论在我们多学科的HF诊所接受治疗的患者中,采用SFL网络降低了STEMI后HF的患病率,并降低了射血分数。

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