Maiden Voyage of the Collaborative Cross Mouse: Exploring Variability in Animals’ Response to Perchloroethylene

摘要

Researchers have spent more than a decade perfecting an alternative laboratory mouse model—the Collaborative Cross (CC)— that is designed to mimic the genetic diversity of the human population. This issue of Environmental Health Perspectives contains the first published toxicology study to be performed with CC mice: an exploration of how the toxic effects of perchloroethylene vary from animal to animal.