Technical feasibility of line-assisted complete closure technique for large mucosal defects after colorectal endoscopic submucosal dissection

摘要

Background and study aims?Complete closure of large mucosal defects after colorectal endoscopic submucosal dissection (C-ESD) is considered impossible in most cases because of the limited width of the open clip.?We therefore invented a simple closure technique using clip-and-line, named “line-assisted complete closure (LACC)”, and assessed its technical feasibility. Patients and methods?Between January and February 2016, we performed LACC in 11 patients after C-ESD and included them in this retrospective feasibility study. Outcome measures were procedural success rate, procedure time, and post-procedural complications. Results?The median size of the resected specimen was 36?mm (range 30?–?72?mm). Procedural success was achieved in 10 of 11 cases (91?%). Those 10 cases required a median of 9 endoclips (range 6?–?12) for complete closure. Median procedure time for LACC was 14 minutes (range 6?–?22). No complications were observed in any of the cases after the procedure. Conclusion?LACC is a simple and feasible technique for complete closure of large mucosal defects after C-ESD.