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首页> 外文期刊>EFSA Journal >Scientific Opinion on the safety and efficacy of Pediococcus pentosaceus (NCIMB 30044) as a silage additive for all animal species
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Scientific Opinion on the safety and efficacy of Pediococcus pentosaceus (NCIMB 30044) as a silage additive for all animal species

机译:关于戊糖小球藻(NCIMB 30044)作为所有动物青贮添加剂的安全性和有效性的科学意见

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Pediococcus pentosaceus is a technological additive intended to improve the ensiling process at a minimum proposed dose of 1 × 108 colony‐forming units (CFU)/kg fresh material. The P. pentosaceus strain was found to be resistant to tetracycline by an unidentified mechanism and thus may pose a risk for the spread of genes coding for resistance to an antibiotic of human and veterinary importance. Thus, the additive containing this strain is not considered safe for the target animals and consumers of products from animals fed the treated silage. The additive should be regarded as a skin and eye irritant and a potential skin and respiratory sensitiser, and treated accordingly. Since the P. pentosaceus strain carries an uncharacterised resistance to tetracycline, the FEEDAP Panel cannot conclude on its safety for the environment. A total of seven studies with laboratory‐scale silos were made using samples of forage of differing water‐soluble carbohydrate content. In each case, replicate silos containing treated forage were compared with identical silos containing the same but untreated forage. The results showed that the additive has the potential to improve the production of silage from easy, moderately difficult and difficult to ensile forage species by reducing the pH and increasing the preservation of dry matter. This was most consistently shown at application rates of 5 × 107 and 1 × 108 CFU/kg forage.
机译:戊糖小球藻是一种技术添加剂,旨在以最小建议剂量1×108个菌落形成单位(CFU)/ kg新鲜材料来改善保鲜过程。通过未知的机制发现了戊糖假单胞菌菌株对四环素具有抗性,因此可能对编码对人类和兽医学重要性的抗生素具有抗性的基因造成风险。因此,认为含有该菌株的添加剂对目标动物和饲喂处理过的青贮饲料的动物产品的消费者不安全。该添加剂应被视为对皮肤和眼睛有刺激性以及潜在的皮肤和呼吸道致敏剂,并应进行相应处理。由于戊糖假单胞菌菌株对四环素具有未表征的抗药性,因此FEEDAP专家组无法就其对环境的安全性得出结论。使用不同水溶性碳水化合物含量的牧草样本,总共进行了七个实验室规模的筒仓研究。在每种情况下,将包含处理过的草料的重复筒仓与包含相同但未处理的草料的相同筒仓进行比较。结果表明,该添加剂具有通过降低pH值和增加干物质的保存来改善青贮饲料的潜力,这些青贮饲料由容易,中等困难和难以驯化的饲料种类组成。在施用量为5×107和1×108 CFU / kg饲草的情况下,最一致地表明了这一点。

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    《EFSA Journal》 |2014年第3期|共12页
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