PLASMA LEVEL OF VITAMIN C IN WOMEN WITH PRE-ECLAMPSIA IN ARDABIL, IRAN

摘要

Background: Pre-eclampsia, a vascular disorder of pregnancy, is a leading cause of maternal morbidity as well as perinatal morbidity and mortality. The cause of pre-eclampsia remains largely unknown. Accumulating evidences from clinical and epidemiological studies suggest that diffuse endothelial dysfunction, resulting from oxidative stress, plays an important role in the pathogenesis of pre-eclampsia. Independent effect of maternal biological markers, such as elevated triglyceride or low plasma vitamin C (ascorbic acid) concentrations are related to increased pre-eclampsia risk.