A fast, simple and convenient procedure for the synthesis of fused pyrimidinone derivatives by using [Hmim][HSO4] as a green, efficient and reusable catalyst under solvent-free conditions

摘要

In the present of methylimidazolium hydrogen sulfate, the synthesis of arylidene heterobicyclic pyrimidinones is studied by condensation of aromatic aldehyde, cyclopentanone, and urea or thiourea. Using solvent-free conditions, non-toxic and inexpensive materials, simple and clean work-up, short reaction times and good yields of the products are the advantages of this method.