This paper presents an effective approach to optimize the reassignment of Human Resources in the enterprise that is formed by several units of productions to take into consideration the human characteristics. This approach consists of two steps; the first step is to formalize the studied problem that is practically take the form of the generalized assignment problem (GAP) known as NP-hard problem. Additionally, the variables in the formulation of our problem are interlinked by certain constraints. These two proprieties can to justify the important complexity of this problem. The second step is focused to solve this complex problem by using the genetic algorithm. We present the experimentally result for justifying the validity of the proposed approach. So, the solution obtained allowed us to get an optimal assignment of personnel that can lead to improve the average productivity or ratability or at least ensure its equilibration within sites of enterprise.
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