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Esophagitis in Children with Celiac Disease

机译:乳糜泻患儿的食管炎

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Objectives.To our knowledge, the occurrence of esophagitis in children with celiac disease (CD) has never been evaluated. The aim of this study is to determine the prevalence of esophagitis in children with CD.Patients and Methods.Between 2003 and 2007, children with biopsy confirmed CD were retrospectively identified. Biopsy reports were reviewed for esophageal inflammation. Biopsy reports of 2218 endoscopies performed during the same period were also evaluated for inflammation.Results.Forty-nine children diagnosed with CD (47% boys). Nineteen of 49 (39%) patients with CD had esophagitis (95% CI 0.23–0.5). Thirty percent of boys and 46% of girls with CD had esophagitis (95% CI 0.12–0.40). Overall, 45% of patients who underwent upper endoscopy had esophagitis. The prevalence of esophagitis in CD (39%) compared to the prevalence of esophagitis (45%) in our practice was not significantly different,P=0.2526.Conclusion.There was no difference in the prevalence of esophagitis between children diagnosed with CD at the time of their diagnostic EGD and the prevalence of esophagitis in children without CD. A prospective study to determine whether the esophagitis should be treated with acid suppression or whether the esophagitis heals with the gluten-free diet is warranted.
机译:目的:据我们所知,从未评估儿童腹腔疾病(CD)患食管炎的情况。本研究的目的是确定患有CD的儿童的食管炎患病率。患者和方法。2003年至2007年间,对经活检证实为CD的儿童进行了回顾性鉴定。对活检报告进行了食管炎症检查。还对同期进行的2218例内窥镜检查的活检报告进行了炎症评估。结果:49名被诊断患有CD的儿童(男童占47%)。 49名CD患者中有19名(39%)患有食管炎(95%CI为0.23-0.5)。患有CD的男孩中有30%,女孩中有46%患有食管炎(95%CI为0.12-0.40)。总体而言,接受内镜检查的患者中有45%患有食管炎。在我们的实践中,CD中的食管炎患病率(39%)与食管炎的患病率(45%)并无显着差异,P = 0.2526。结论。无CD患儿诊断EGD的时间和食管炎的患病率。一项前瞻性研究,以确定是否应通过抑制酸治疗食道炎或是否应通过无麸质饮食来治愈食道炎。

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