EVALUATION OF WOUND HEALING ACTIVITY OF HEXANE AND METHANOLIC EXTRACT OF FRUIT PULP OF MOMORDICA BALSAMINA. LINN IN ALBINO RATS

摘要

Wound. healing.is.an.important. process.which. is. the.basis.of. various.surgical. manipulations.. Restoration.of.damaged.tissue,.wound.or.facture.is.an.important.process.which.plays.vital.role.in.survival.of.life..Momordica. balsamina. Linn. (Cucurbitaceae). is. a. monoecious,. very. slender,. branched,. grooved,. sub.glabrous. tendrils.. It. has. tremendous. medicinal. values. such. as. leprosy,. piles,. jaundice. etc.,. The. present.study.was.undertaken.on.hexane.and.methanolic.extract.of.fruit. pulp. of. M.balsamina. on. wound. healing.activity. through. oral. and. topical. routes. on. excision. wound. model..The.activity.was.compared.with.standard. drug. Ciprofloxacin. (10. mg/kg). and. Povidone. iodine. ointment.(5%.w/w).respectively..The.hexane.extract.was.found.to.have.better.wound.healing.effect.than.methanolic.extract.on.both.route.of.administration.and.the.oral.route.of.administration.shows.faster. rate. of. healing. when. compared. with.topical.application