IN VITRO ANTIOXIDANT AND ANTICHOLINESTERASE ACTIVITIES OF GARCINIA COMBOGIA

摘要

The. present.study. evaluated. the. free. radical. scavenging. and.anticholinesterase. activity. of.the. water. extracts. of. Garcinia. combogia.(WEGC). fruit.rinds. in.vitro..The.antioxidant.activity.of.WEGC.was.evaluated.by.using.the.free.radical.scavenging.activity.assay.(DPPH.method),.hydroxyl.radical.scavenging. activity,.ferric. reducing.antioxidant. potential,.total.peroxy.radical.trapping.potential.and.lipid.peroxidation.activity...In.addition,. total.phenolic.(TP).and.total.flavonoid.was.determined.by.using.pyrocatechol.and.quercetin.as.a.standard..The.anticholinesterase.activity.of.WEGC.was.significantly. lower.than.neostigmine,.a. standard. drug..Furthermore,.a. significant.correlation.between.the. total. phenolic.content,.antioxidant. and.anticholinesterase. activities. of. both. the. extracts. indicating. that. total. phenolics. might. be. responsible. for. the. observed. antioxidant. and.anticholinesterase.activities.This.is.the.first.report.in.this.direction