PHYTOCHEMICAL, ANTIMICROBIAL EVALUATION AND DETERMINATION OF TOTAL PHENOLIC AND FALVONOID CONTENTS OF SESBANIA GRANDIFLORA FLOWER EXTRACT

摘要

Sesbanial grandiflora used in traditional klowledge of ayurveda for various diseases and infections. The acetone (70%) extrac tion was carried out on the flowers of the plant. The phytochemical groups were identified by the tests of characterization, and then quantified by the tests of proportioning of total phenolics and flavonoides. The total flavonoids and phenolic contents were also quantified in acetone extract of flower part. This activity is related to pheno lic compo unds contained in the extracts. The total polyphenolic content in the flower extract found to be 49.1+0.96 mcg/mg and flavonoid content was 12.86+0.72 mcg/mg. Extracts also expressed a good antibacterial activity. The flowers extract FE 200 showed highest inhibition against P. aerugunosa (25.00 ± 0.60 mm), S. aureus (21.00 ± 0.50 mm) and E. coli (19.00±0.60), which are especially responsible for ophthalmic infection, conjunc tivitis