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首页> 外文期刊>International Journal of Pharmacy and Pharmaceutical Sciences >NOSOCOMIAL INFECTION BY NON-FERMENTING GRAM NEGATIVE BACILLI IN TERTIARY CARE HOSPITAL: SCREENING AND CURE
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NOSOCOMIAL INFECTION BY NON-FERMENTING GRAM NEGATIVE BACILLI IN TERTIARY CARE HOSPITAL: SCREENING AND CURE

机译:非发酵革兰阴性杆菌在三级医院的医院感染:筛查和治疗

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Objective: The purpose of the present study was to identify the Non-Fermenting Gram Negative Bacteria from the tertiary care hospital. Methods: The conventional method was used i.e. Antibiotic susceptibility test which was performed by Kirby–Bauer disc diffusion method and analysis of microbes was done by Vitek-2. Results: 172 samples were identified as Non-Fermenting Gram-Negative Bacilli from 1526 respiratory samples. Acinetobacter baumanii was the predominant isolate accounting 103 (59.88%) specimens followed by Pseudomonas aeruginosa 33.13%. Other isolates were Stenotrophomonas maltophilia 5.23% and Burkholderi acepacia 1.74%. From the 172 samples, Endotracheal Aspirate was found to be the most infected amongst all the other samples. Acinetobacter baumanii and Pseudomonas aeruginosa were the most common NFGNB isolated in our study from patients of Respiratory Tract Infections. Conclusion: Both Acinetobacter baumanii and Pseudomonas aeruginosa showed good sensitivity to colistin, amikacin, cefoperazone while in most cases carbapenam is found to be highly resistant. Colistin along with amikacin and cefoperazone should be used against this pathogen for treatment. Keywords: Nosocomial infection, Gram negative bacilli, Tertiary care hospital, Lower respiratory tract infection, Non-fermenting bacilli
机译:目的:本研究的目的是确定三级护理医院的非发酵革兰氏阴性细菌。方法:采用常规方法,即用Kirby-Bauer纸片扩散法进行抗生素药敏试验,并用Vitek-2进行微生物分析。结果:从1526份呼吸道样本中鉴定出172份样本为非发酵革兰阴性杆菌。鲍曼不动杆菌为主要分离物,占103个(59.88%)标本,其次是铜绿假单胞菌,占33.13%。其他分离株是嗜麦芽窄食单胞菌5.23%和伯克霍尔德菌醋栗1.74%。从172个样本中,发现气管内吸出物是所有其他样本中感染最严重的。鲍曼不动杆菌和铜绿假单胞菌是我们研究中从呼吸道感染患者中分离出的最常见的NFGNB。结论:鲍曼不动杆菌和铜绿假单胞菌均对粘菌素,丁胺卡那霉素,头孢哌酮具有良好的敏感性,而在大多数情况下,卡巴培南具有很高的耐药性。 Colistin与阿米卡星和头孢哌酮一起应用于治疗该病原体。关键词:医院感染,革兰氏阴性杆菌,三级医院,下呼吸道感染,非发酵菌

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