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Active case-finding for tuberculosis by mobile teams in Myanmar: yield and treatment outcomes

机译:缅甸流动工作队积极寻找结核病病例:产量和治疗结果

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BackgroundSince 2005, the Myanmar National Tuberculosis Programme (NTP) has been implementing active case finding (ACF) activities involving mobile teams in hard-to-reach areas. This study revealed the contribution of mobile team activities to total tuberculosis (TB) case detection, characteristics of TB patients detected by mobile teams and their treatment outcomes. MethodsThis was a descriptive study using routine programme data between October 2014 and December 2014. Mobile team activities were a one-stop service and included portable digital chest radiography (CXR) and microscopy of two sputum samples. The algorithm of the case detection included screening patients by symptoms, then by CXR followed by sputum microscopy for confirmation. Diagnosed patients were started on treatment and followed until a final outcome was ascertained. ResultsA total of 9 349 people with symptoms suggestive of TB were screened by CXR, with an uptake of 96.6%. Of those who were meant to undergo sputum smear microscopy, 51.4% had sputum examinations. Finally, 504?TB patients were identified by the mobile teams and the overall contribution to total TB case detection in the respective townships was 25.3%. Among total cases examined by microscopy, 6.4% were sputum smear positive TB. Treatment success rate was high as 91.8% in study townships compared to national rate 85% (2014 cohort). ConclusionsThis study confirmed the feasibility and acceptability of ACF by mobile teams in hard-to-reach contexts, especially when equipped with portable, digital CXR machines that provided immediate results. However, the follow-up process of sputum examination created a significant barrier to confirmation of the diagnosis. In order to optimize the ACF through mobile team activity, future ACF activities were needed to be strengthened one stop service including molecular diagnostics or provision of sputum cups to all presumptive TB cases prior to CXR and testing if CXR suggestive of TB.
机译:背景技术自2005年以来,缅甸国家结核病计划(NTP)一直在开展积极的病例调查(ACF)活动,涉及难以到达地区的机动团队。这项研究揭示了流动团队活动对总结核病病例检测,流动团队检测到的结核病患者特征及其治疗结果的贡献。方法这是一项描述性研究,使用2014年10月至2014年12月之间的常规程序数据。流动团队的活动是一站式服务,包括便携式数字胸片(CXR)和两个痰标本的显微镜检查。病例检测算法包括按症状筛查患者,然后进行CXR筛查,然后进行痰镜检查以确诊。被诊断的患者开始接受治疗,直至确定​​最终结果。结果CXR筛查了9 349例提示结核病症状的人群,摄取率为96.6%。在准备进行痰涂片显微镜检查的人中,有51.4%进行了痰检查。最终,流动小组确定了504?TB患者,在各个乡镇对总TB病例检测的总体贡献为25.3%。在所有经显微镜检查的病例中,有6.4%为痰涂片阳性结核。研究乡镇的治疗成功率高达91.8%,而全国的这一比率为85%(2014年同期)。结论这项研究证实了移动团队在难以到达的环境中进行ACF的可行性和可接受性,尤其是在配备便携式数字CXR机器并提供即时结果的情况下。但是,痰液检查的后续过程为确认诊断创造了很大的障碍。为了通过流动团队活动优化ACF,需要加强未来的ACF活动,包括一站式服务,包括在CXR之前对所有假定的TB病例进行分子诊断或提供痰杯,并测试CXR是否提示结核病。

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