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Endophytic Fungi: A Review on Pharmacological Activities and Its Industrial Application

机译:内生真菌:药理活性及其工业应用综述

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Endophytic fungi isolated from different parts of plants have a more beneficial effect and therefore endophytes can be used in various applications. As Endophytes living inside the plants increases the resistance capacity of the plant towards undesirable microbial attacks and stresses. The secondary metabolites like alkaloids, indole derivatives, steroids, terpenoids, quinones, flavonoids produced by these fungi show antimicrobial, insecticidal, cytotoxic and anticancer activities. Substances that are producing by endophytes have promising role in modern medicine, agricultural field and also in industries as like an antibiotic, anticancer and anti-diabetic compounds for the treatment of several diseases in human and animals. Nowadays researchers have unique attention on endophytic fungi because of its ability to generate an excellent number of new and interesting bioactive metabolites, which plays a significant role in pharmaceutical, industrial and agricultural importance. The present review contains a wide range of information about the application of endophytic fungi in various fields and also its implications for drug development.
机译:从植物不同部位分离的内生真菌具有更有益的作用,因此内生菌可用于多种应用。由于生活在植物内部的内生菌增加了植物对不希望的微生物侵袭和胁迫的抵抗能力。这些真菌产生的次生代谢物(如生物碱,吲哚衍生物,类固醇,萜类,醌,类黄酮)具有抗菌,杀虫,细胞毒性和抗癌活性。由内生菌产生的物质在现代医学,农业领域以及在诸如抗生素,抗癌药和抗糖尿病化合物等行业中具有广阔的前景,可用于治疗人类和动物的多种疾病。如今,研究人员对内生真菌有着独特的关注,因为它能够产生大量新的有趣的生物活性代谢产物,而这些代谢产物在制药,工业和农业方面都起着重要作用。本综述包含有关内生真菌在各个领域中的应用及其对药物开发的影响的广泛信息。

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