A Comparison of the Long-Term (1 year) Lipid Modifying Effects of D-003 (Sugarcane Wax Acids) and Policosanol: A Randomized, Double-Blind Study”

摘要

Patient compliance and safety is of prime importance in case of any drug delivery system. As safety is concern, natural polymers are always better than synthetic and semisynthetic polymers. The reason behind this fact is that all natural polymers are either biodegradable or biocompatible. Unlike synthetic polymers, they are nontoxic, noncarcinogenic and most admiringly ecofriendly. Tamarind Seed Polysaccharide (TSP) is one of such natural polymer which is obtained from seeds of Tamarindus indica. Isolation and characterization of TSP involves simple techniques resulting in lucrative yield in its production. In order to improve the physicochemical properties like heat stability TSP is modified either by physical or chemical method. High drug holding capacity, high swelling index, high thermal stability and improved shelf life are some valuable properties of modified TSP. Due to these remarkable properties TSP has wide range of application from food industry to pharma industry.