Environmentally Benign Ultrasound Promoted Synthesis of Some Important Pyrazoline Derivatives as Antibacterial and Antifungal Agents

摘要

A new series of pyrazoline derivatives (4a-f) has been synthesized by ultrasonication methods and evaluated for its antibacterial and antifungal activity. The chalcones (3a-f) were transformed into respective pyrazoline derivatives by using hydrazine hydrate and few drops of glacial acetic acid in ethanol. All the synthesized compounds were confirmed by FTIR, 1HNMR and mass spectral data.