Acute High Intensity Anaerobic Training and Rhabdomyolysis Risk

摘要

The current popularity of high intensity anaerobic training has caused concerns over the safety and prevalence of conditions such as rhabdomyolysis; thus it is important to understand the possible risks of participating in this type of activity. The purpose of this study was to determine the magnitude of muscle damage associated with a single high intensity anaerobic training session, and the relationship of this response to markers of fitness. Fifteen recreationally trained male participants (age 22.9 ± 4.3 y, mass 87.3 ± 15.6 kg, body fat 16.8 ± 6.4%, VO2 peak 50.1 ± 7.2 ml · kg-1 · min-1 ) completed a single anaerobic training session consisting of high intensity plyometrics and calisthenics. Prior to the exercise session, participants completed a maximal aerobic capacity test, body composition analysis, and a military physical fitness test (1 min push-ups, 54 ± 14; 1 min sit-ups, 45 ± 11; 1.5 mile run, 12:17 ± 0.067 min). Serum creatine kinase (CK) was measured prior to and 48 h following the exercise session. CK at 48 h (126.3 ± 68.9 U· L-1) did not reach the limits indicating rhabdomyolysis (~881-1479 U/L) but was elevated above resting (CK resting 90.5 ± 53.4). VO2 peak (L · m-1) had a positive correlation with CK levels (r = .51; p < 0.05) but body mass or any other indicator of fitness did not correlate. An increase in serum CK levels occurred, but did not reach levels of rhabdomyolysis, suggesting that a single high intensity exercise session is safe for healthy individuals who exercise regularly.