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Prevalence and Predictors of Malaria in Human Immunodeficiency Virus Infected Patients in Beira, Mozambique

机译:莫桑比克贝拉的人类免疫缺陷病毒感染患者的疟疾患病率和预测因素

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Co-infection between malaria and HIV has major public health implications. The aims of this study were to assess the malaria prevalence and to identify predictors of positivity to malaria Test in HIV positive patients admitted to the health center S?o Lucas of Beira, Mozambique. A retrospective cross-sectional study was performed from January 2016 to December 2016. Overall, 701 adult HIV patients were enrolled, positivity to malaria test was found in 232 (33.0%). These patients were found to be more frequently unemployed (76.3%), aged under 40 (72.0%), with a HIV positive partner (22.4%) and with a CD4 cell count 200 (59.9%). The following variables were predictors of malaria: age under 40 (O.R. = 1.56; 95%CI: 1.22–2.08), being unemployed (O.R. = 1.74; 95%CI: 1.24–2.21), irregularity of cotrimoxazole prophylaxis’s (O.R. = 1.42; 95%CI: 1.10–1.78), CD4 cell count 200 (O.R. = 2.01; 95%CI: 1.42–2.32) and tuberculosis comorbidity (O.R. = 1.58; 95%CI: 1.17–2.79). In conclusion, high malaria prevalence was found in HIV patients accessing the out-patients centre of S?o Lucas of Beira. Our findings allowed us to identify the profile of HIV patients needing more medical attention: young adults, unemployed, with a low CD4 cell count and irregularly accessing to ART and cotrimoxazole prophylaxis.
机译:疟疾和艾滋病毒之间的共同感染具有重大的公共卫生影响。本研究的目的是评估莫桑比克贝拉健康中心S?o Lucas收治的HIV阳性患者的疟疾流行率,并确定疟疾检测阳性的预测因素。从2016年1月至2016年12月进行了一项回顾性横断面研究。总共招募了701名成年HIV患者,其中232人(33.0%)对疟疾检测呈阳性。发现这些患者的失业率更高(76.3%),年龄在40岁以下(72.0%),HIV阳性伴侣(22.4%),CD4细胞计数<200(59.9%)。以下变量是疟疾的预测因子:40岁以下(OR = 1.56; 95%CI:1.22-2.08),失业(OR = 1.74; 95%CI:1.24-2.21),cotrimoxazole预防措施不规则(OR = 1.42; 95%CI:1.10–1.78),CD4细胞计数<200(OR = 2.01; 95%CI:1.42–2.32)和结核合并症(OR = 1.58; 95%CI:1.17–2.79)。总之,在进入贝拉圣卢卡斯门诊中心的艾滋病毒感染者中发现疟疾高发。我们的发现使我们能够确定需要更多医疗护理的HIV患者的特征:未成年人,失业,CD4细胞计数低,不规律地使用抗逆转录病毒疗法和来曲唑预防。

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