An Electrochemical Sensitive Sensor for Determining Sulfamethoxazole Using a Modified Electrode Based on Biosynthesized NiO Nanoparticles Paste Electrode

摘要

In this research, we describe a new type of sulfamethoxazole electrochemical sensor based on a carbonpaste electrode (CPE) modified with NiO nanoparticle (NiO-NPs) and 1-methyl-3-octylimidazoliumtetrafluoroborate (1M3OIMZTFB). The NiO nanoparticle was biosynthesized with a diameter of ? 18.0nm by Mentha aquatic extract and characterized by AFM, FESEM, XRD and EDS methods. Theoxidation peak of sulfamethoxazole was recorded at +1130 mV and +995 mV at surface of CPE and1M3OIMZTFB/NiO-NPs/CPE. Meanwhile, the oxidation signal of sulfamethoxazole was improved by~20.32 times compared to unmodified CPE. The 1M3OIMZTFB/NiO-NPs/CPE exhibited good catalyticactivity toward sulfamethoxazole with a dynamic range 0.003-400.0 μM and limit of detection 1.0 nM.The 1M3OIMZTFB/NiO-NPs/CPE was used as useful tool for determination of sulfamethoxazole inreal samples.