Proliferative Inhibition and Apoptotic Mechanism on Human Non-small-cell Lung Cancer (A549 Cells) of a Novel Cucurbitacin from Wilbrandia ebracteata Cogn

I.T. Silva; Marina R. Teixeira; Karen L. Lang; Tatiana da R. Guimaraes; Sabine E. Dudek; Fernando J. Duran; Stephan Ludwig; Miguel S.B. Caro; Eloir P. Schenkel; Claudia M.O. Simoes

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Proliferative Inhibition and Apoptotic Mechanism on Human Non-small-cell Lung Cancer (A549 Cells) of a Novel Cucurbitacin from Wilbrandia ebracteata Cogn

机译：一种新的Wilbrandia ebracteata Cogn葫芦素对人非小细胞肺癌（A549细胞）的增殖抑制和凋亡机制

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Cancer represents a major public health problem from all over the world and the lung carcinoma is the leading cause of cancer death. In this sense, the aim of the present study was to examine the cytotoxic effects of a novel Cucurbitacin (Cuc1) isolated f

机译：癌症是世界范围内的主要公共卫生问题，肺癌是导致癌症死亡的主要原因。从这个意义上讲，本研究的目的是研究新型葫芦素（Cuc1）分离的f

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《International Journal of Cancer Research》 |2013年第2期|共15页
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I.T. Silva; Marina R. Teixeira; Karen L. Lang; Tatiana da R. Guimaraes; Sabine E. Dudek; Fernando J. Duran; Stephan Ludwig; Miguel S.B. Caro; Eloir P. Schenkel; Claudia M.O. Simoes;
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1. The proliferative inhibition and apoptotic mechanism of Saikosaponin D in human non-small cell lung cancer A549 cells. [J] . Hsu YL, Kuo PL, Lin CC Life sciences . 2004,第10期

机译：皂苷D在人非小细胞肺癌A549细胞中的增殖抑制及凋亡机制。
2. Timosaponin AIII inhibits migration and invasion of A549 human non-small-cell lung cancer cells via attenuations of MMP-2 and MMP-9 by inhibitions of ERK1/2, Src/FAK and beta-catenin signaling pathways [J] . Jung Okkeun, Lee Jongsung, Lee Yu Jin, Bioorganic and Medicinal Chemistry Letters . 2016,第16期

机译：Timosaponin AIII通过抑制ERK1 / 2，Src / FAK和β-catenin信号通路来抑制MMP-2和MMP-9，从而抑制A549人非小细胞肺癌的迁移和侵袭。
3. Proliferative inhibition, cell-cycle dysregulation, and induction of apoptosis by ursolic acid in human non-small cell lung cancer A549 cells [J] . Hsu YL, Kuo PL, Lin CC Life sciences . 2004,第19期

机译：熊果酸对人非小细胞肺癌A549细胞的增殖抑制，细胞周期失调和凋亡诱导
4. The Proliferative Inhibition and Apoptotic Mechanism of Saikosaponin D in Human Non-Small Cell Lung Cancer A549 Cells [C] . Jiang Dong, Yang Ru-song, Zheng Shi-ying, Bioinformatics and Biomedical Engineering , 2009. ICBBE 2009 . 2009

机译：皂苷D在人非小细胞肺癌A549细胞中的增殖抑制及其凋亡机制
5. Pharmacology Profiles of ALK and FLT3 Kinase Inhibitors against Non-Small-Cell Lung Cancer Cells and Acute Myeloid Leukemia Cells with Cancer Driver Mutations [D] . 森政道 2019

机译：ALK和FLT3激酶抑制剂对非小细胞肺癌细胞和急性髓系白血病细胞的癌症驱动突变的药理作用
6. Cucurbitacin B inhibits proliferation and induces apoptosis via STAT3 pathway inhibition in A549 lung cancer cells [O] . MENG ZHANG, ZHI-GANG BIAN, YI ZHANG, -1

机译：葫芦素B通过抑制STAT3途径抑制A549肺癌细胞增殖并诱导凋亡
7. Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells [O] . Hao He, Chang Xu, Lei Zheng, 2019

机译：Polyphyllin VII通过抑制A549人肺癌细胞的PI3K / AKT和NF-κB途径诱导凋亡细胞死亡

Proliferative Inhibition and Apoptotic Mechanism on Human Non-small-cell Lung Cancer (A549 Cells) of a Novel Cucurbitacin from Wilbrandia ebracteata Cogn

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