Significance of Cyclin D1 Overexpression and Amplification in Ductal Hyperplasia, Carcinoma in situ and Invasive Carcinoma in Egyptian Female Breast

摘要

Cyclin D1 is involved in regulating the transition of G1 to S-phase in the cell cycle. Amplification and overexpression of the cyclin D1 gene have been reported to be implicated in breast carcinoma and are suggested to play important roles in breast carci