The histopathological study of granulomatous diseases in various organ to find the exact etiology of granulomas

摘要

This study was conducted to find out the etiology of all granulomatous lesions on Histo-pathology and Cytological studies. Our study was done at SBKS MI & RC, Piparia from January 2011 to July 2012. All the cases which were clinically diagnosed and suspected of granulomas, on haematoxylin and eosin stained sections were studied. Special stains like Ziehl Neelsen stain, PAS stain and Fite Faraco stain were done whenever required. The morphological features and special staining helped us to find the specific etiology of Granulomas in 123 cases whereas it could not be determined in 7 cases even after special stains. Thus we conclude that Cytological study of granulomatous lesions helped us to find the exact etiology of Granulomas in 81% of cases whereas Histopathological examination of granulomatous lesions helped us to find the exact etiology of Granulomas in 95 % of cases. The correlation of histo-pathology with PCR, serological tests and culture correlation would have helped to find the specific etiology in the remaining cases