Prevalence and Antibiotic profile of Non fermenters at tertiary care hospital, Surat

摘要

Introduction: Non fermenters are omnipresent in nature like soil, water, plants, decaying vegetations, food stuffs and normal flora of human. Their pathogenic potential has been well established by their frequent isolation from clinical samples and their association with clinical diseases. In last few years problem is increased by the emergence of resistance to antimicrobial agents which are widely used against the non fermenters, making them as an important health care associated pathogen. Objectives: To see prevalence and antibiotic susceptibility of non fermenters in tertiary care hospital, Surat to guide health care management. Methods: It was a prospective observational analytical study in which patients with isolated non fermenters from various clinical samples received by Microbiology department were enrolled. Samples were processed according to standard guidelines. Isolates were identified with different biochemical reactions and antibiotic susceptibility testing was performed on Muller hinton agar by Kirby bauer disc diffusion method. The results were interpreted according to CLSI guidelines 2017. Results: Total 157 isolates were obtained. A. baumannii was the most common organism isolated followed by P. aeruginosa . The mean age group was 15-29 years with male preponderance. The sensitivity showed complete sensitivity to only Polymyxin group of drugs with 2nd highest sensitive group Carbapenems. Conclusions: The present study highlighted the fact that non fermenter gram negative bacilli are emerging as important pathogens and shows resistance to commonly used antibiotics, so rapid identification should be done for appropriate patient care.