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Extensive intramedullary schwannoma of the sub-axial cervical spine – A case report

机译:亚轴颈椎广泛性髓内神经鞘瘤-病例报告

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Spinal schwannomas originate from Schwann cells and as a group represent 30% of spinal cord tumors. These lesions are commonly intra-dural extramedullary in location and in fact purely intramedullary schwannomas of the spinal cord represent only 1.1% of spinal schwannomas. Almost all of these occur in patients with Neurofibromatosis. Approximately 50 cases of intramedullary schwannomas not related to neurofibromatosis have been described to date.This case report gives an account of a young male patient with no family history nor clinical signs of Neurofibromatosis whom presented to out institution with an extensive schwannoma of his sub-axial cervical spinal cord extending from C4-T2. Neurological examination of his upper limbs on manual muscle testing revealed normal shoulder and elbow power 5/5, weakness of wrist dorsiflexion 3/5 and wasting of his intrinsic hand muscles bilaterally also with power 3/5. His lower limb examination revealed an incomplete T4 sensory level with preserved sensation and on manual muscle testing no motor function 0/5 was present. Under neurophysiological monitoring he was taken to theatre where the intra-operative finding of the schwannoma being subpial and intramedullary was confirmed. A gross total resection was achieved and post operatively his upper limb function showed no deterioration and his lower limb function showed improvement.This case report gives an account of a young male patient whom presented to our department with an extensive intramedullary schwannoma of his cervical spine extending from C4-T2. The surgical management resulted in clinical improvement and prevented ascending motor weakness.
机译:脊髓神经鞘瘤起源于雪旺氏细胞,作为一组,占脊髓肿瘤的30%。这些病变通常位于硬膜内髓外,实际上,仅脊髓的髓内神经鞘瘤仅占脊髓神经鞘瘤的1.1%。这些几乎全部发生在神经纤维瘤病患者中。迄今已描述了约50例与神经纤维瘤病无关的髓内神经鞘瘤。该病例报告描述了一位年轻男性患者,既无家族病史,也没有神经纤维瘤病的临床体征,他被诊治到其广泛的亚轴神经鞘瘤颈脊髓从C4-T2延伸。对他的上肢进行人工肌肉测试的神经系统检查显示正常的肩部和肘部力量为5/5,腕背屈无力3/5,双侧内在手部肌肉的消耗也为力量3/5。他的下肢检查发现T4感觉水平不完整,但感觉保持不变,在手动肌肉测试中,没有运动功能0/5。在神经生理学监测下,他被送往战区,在手术中发现了神经鞘瘤为椎下和髓内的发现。该病例报告描述了一名年轻男性患者,该患者向我科诊治,其颈椎椎弓根扩大性髓内神经鞘瘤扩大,该患者报告了全部切除,并且术后上肢功能未见恶化,下肢功能有所改善。来自C4-T2。外科手术治疗改善了临床症状,并预防了运动能力下降。

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