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Interim estimates of the effectiveness of influenza vaccination against influenza‐associated hospitalization in children in Hong Kong, 2015–16

机译:2015-16年香港儿童流感疫苗接种对流感相关住院治疗的有效性的临时估计

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Abstract From 1 September 2015 through 31 January 2016, we enrolled 2068 children 6?months to 17?years of age admitted to hospital with a febrile acute respiratory infection in our test-negative study. Information on receipt of 2015–16 northern hemisphere inactivated influenza vaccination was elicited from parents or legal guardians. Using conditional logistic regression adjusting for age and matching on calendar time, we estimated influenza vaccine effectiveness against hospitalization with influenza A or B to be 79.2% (95% confidence interval: 42.0%–92.4%). Annual influenza vaccination should be more widely used in children in Hong Kong.
机译:摘要从2015年9月1日至2016年1月31日,我们在试验阴性研究中招募了2068名6个月至17岁的住院患者,他们因发热性急性呼吸道感染入院。从父母或法定监护人那里获得了关于2015-16年北半球灭活流感疫苗接种情况的信息。通过对年龄进行调整并与日历时间匹配的条件逻辑回归,我们估计针对A或B型流感住院的流感疫苗有效性为79.2%(95%置信区间:42.0%–92.4%)。每年应在香港儿童中广泛使用年度流感疫苗接种。

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