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Vancomycin resistant enterococci in farm animals – occurrence and importance

机译:耐万古霉素的肠球菌在农场动物中的发生和重要性

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The view on enterococci has over the years shifted from harmless commensals to opportunistic but important pathogens mainly causing nosocomial infections. One important part of this development is the emergence of vancomycin resistance enterococci (VRE). The term VRE includes several combinations of bacterial species and resistance genes of which the most clinically important is Enterococcus faecium with vanA type vancomycin resistance. This variant is also the most common VRE among farm animals. The reason for VRE being present among farm animals is selection by extensive use of the vancomycin analog avoparcin for growth promotion. Once the use of avoparcin was discontinued, the prevalence of VRE among farm animals decreased. However, VRE are still present among farm animals and by spread via food products they could potentially have a negative impact on public health. This review is based on the PhD thesis Vancomycin Resistant Enterococci in Swedish Broilers – Emergence, Epidemiology and Elimination and makes a short summary of VRE in humans and food producing animals. The specific situation regarding VRE in Swedish broiler production is also mentioned.
机译:多年来,对肠球菌的看法已从无害的观点转变为主要引起医院感染的机会主义但重要的病原体。这一发展的重要部分是万古霉素耐药性肠球菌(VRE)的出现。术语VRE包括细菌种类和耐药基因的几种组合,其中临床上最重要的是粪便肠球菌对vanA型万古霉素耐药。该变体也是农场动物中最常见的VRE。在农场动物中存在VRE的原因是通过广泛使用万古霉素类似物阿伏巴星来促进生长的选择。一旦停止使用阿伏霉素,农场动物中VRE的患病率就会下降。但是,VRE仍存在于家畜中,并且通过食品传播可能会对公众健康产生负面影响。这篇综述是基于瑞典肉鸡抗万古霉素肠球菌的博士学位论文-出现,流行病学和消除,并对人类和产粮动物的VRE作了简短总结。还提到了瑞典肉鸡生产中VRE的具体情况。

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