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Civil construction work: The unseen contributor to the occupational and global disease burden

机译:土木建筑工作:造成职业和全球疾病负担的未知因素

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Background: Construction industry is the second largest employment giving industry in India with many semi-skilled or unskilled workers taking up the occupation for livelihood without any training and proper guidance. Aim: To evaluate the pathogenic association of cement exposure to occupational contact dermatoses as evidenced by immune markers and to correlate their pulmonary functions with years of exposure to cement. Setting and Design: This was a cross-sectional study conducted among randomly selected cement workers. Methods and material: Evaluation of socioeconomic status (SES) and years of exposure of cement workers was done using a questionnaire. Clinical examination of skin lesions and strip patch test with application of potassium dichromate on unexposed skin was performed. Results were interpreted after 48 hours. Absolute eosinophil count (AEC) and IgE levels measured, and spirometric evaluation was performed. Statistical Analysis: Analysis of variance and Pearson's correlation test were used for data analysis. P Results: Clinically, skin lesions were noticed in 51%, elevated AEC in 47%, and raised Anti IgE in 73%. Two participants developed positive reactions to the skin strip patch test. Duration of exposure to cement and SES were compared with clinical skin lesions. Spirometry result was normal in 81%, obstruction in 8%, restriction in 10%, and mixed pattern in 1%. Forced expiratory volume at 1.0 second, forced expiratory flow (25-75%), and (PEFR) Peak Expiratory Flow Rate were markedly reduced with years of exposure. Workers who had greater skin lesions and with increase in exposure had increased AEC and IgE levels, although statistically not significant. Conclusions: Exposure to cement and poor SES is strongly correlated to increased prevalence of skin lesions and reduced pulmonary functions.
机译:背景:建筑业是印度第二大就业机会提供产业,许多半熟练或非熟练工人在没有任何培训和适当指导的情况下从事谋生工作。目的:通过免疫标记物评估水泥接触职业性接触性皮肤病的病原学关联,并将其肺功能与水泥接触年限相关联。设置与设计:这是对随机选择的水泥工人进行的横断面研究。方法和材料:使用问卷调查法评估了社会经济地位(SES)和水泥工人的工作年限。进行皮肤损伤的临床检查,并在未裸露的皮肤上使用重铬酸钾进行剥离试验。 48小时后解释结果。测量绝对嗜酸性粒细胞计数(AEC)和IgE水平,并进行肺量计评估。统计分析:方差分析和皮尔逊相关检验用于数据分析。 P结果:在临床上,发现皮肤病变的比例为51%,AEC升高的比例为47%,抗IgE升高的比例为73%。两名参与者对皮肤条斑测试产生了积极的反应。将接触水泥和SES的持续时间与临床皮肤病变进行了比较。肺活量测定结果正常(81%),阻塞(8%),限制(10%)和混合型(1%)。随着暴露时间的延长,在1.0秒时的强制呼气量,强制呼气流量(25-75%)和(PEFR)峰值呼气流速明显降低。尽管在统计学上不显着,但皮肤病变更大且暴露量增加的工人的AEC和​​IgE水平升高。结论:暴露于骨水泥和不良的SES与皮肤病变的患病率增加和肺功能下降密切相关。

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