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Total enbloc spondylectomy for metastatic high grade spinal tumors: Early results

机译:整体式全脊椎切除术治疗转移性高等级脊柱肿瘤:早期结果

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Background: High grade metastatic spinal tumors are most common and are invasive. These patients can succumb to disease progression if not treated timely. Although considered as invasive and morbid, total enbloc spondylectomy (TES) in selected cases has better survival rates. The authors describe the results of TES for high grade metastatic spinal tumors. Materials and Methods: Five patients (four females and one male) underwent TES for solitary metastatic vertebral lesion between November 2012 and January 2014. These patients presented to us with spinal instability, unrelenting severe spinal pain and/or with severe progressive radiculopathy. Average age was 46.2 years (range 39–62 years). After complete investigations, computed tomography scan, magnetic resonance imaging scan and positron emission tomography (PET) scan, it was confirmed that these patients had high grade solitary vertebral metastatic tumor. Results: Average duration of followup was 18 months (range 16–20 months). The average preoperative visual analog scale score of 9.4 (range 9–10) improved to 2 (range 1–4) at last followup. Average blood loss was 1440 mL (range 1000–2000 mL). Average duration of surgery was 198 min (range 180–240 min). Significant pain relief was noticed in each patient in the immediate postoperative period and during followups. These patients attained complete functional activities of daily living with in a month. The imaging showed implants in situ , no recurrence of tumor, and no activity on PET scan at the final followup. Conclusion: The present series shows favorable short term results of TES for solitary, metastatic, high grade vertebral body tumors by a team approach.
机译:背景:高度转移性脊柱肿瘤是最常见的并且是浸润性的。如果不及时治疗,这些患者可屈服于疾病进展。尽管被认为是侵入性的和病态的,但在部分病例中进行全脊椎切除术(TES)具有更好的生存率。作者描述了TES对高度转移性脊柱肿瘤的结果。材料和方法:2012年11月至2014年1月间,对5例患者(4例女性和1例男性)进行了TES的孤立性转移性椎体病变。这些患者向我们展示了脊柱不稳定,持续的剧烈脊柱疼痛和/或严重的进行性神经根病。平均年龄为46.2岁(39-62岁)。经过全面的检查,计算机断层扫描,磁共振成像扫描和正电子发射断层扫描(PET)扫描,证实这些患者患有高度孤立性椎骨转移性肿瘤。结果:平均随访时间为18个月(范围16–20个月)。术前平均视觉模拟量表评分为9.4(范围9-10),在最后一次随访时提高到2(范围1-4)。平均失血量为1440 mL(范围为1000–2000 mL)。平均手术时间为198分钟(180-240分钟)。术后即刻及随访期间,每位患者均发现疼痛明显缓解。这些患者在一个月内就完成了日常生活的全部功能活动。影像学检查显示原位植入物,无肿瘤复发,最后一次随访时PET扫描无活性。结论:本系列研究通过团队方法显示了TES对孤立,转移,高等级椎体肿瘤的近期良好疗效。

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