Primary osteosarcoma of the breast is a very rare and aggressive entity, which is histologically indistinguishable from conventional osteosarcoma of the bone and other extraskeletal site [1].Carcinoma is the most common malignancy of the breast. Extra-skeletal osteosarcomas have been reported in many tissues of the body including thyroid gland, kidneys, bladder, colon, heart, testes and penis [2–8].When it occurs in the breast, it originates either from normal breast tissue de novo, or as metaplastic differentiation of a primary benign or malignant breast lesion. We reports a case of primary osteogenic sarcoma of breast
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