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Spondylodiskitis and endocarditis due to Streptococcus gordonii

机译:戈登链球菌引起的脊椎盘状炎和心内膜炎

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Background Streptococcus gordonii is an infrequent cause of infective endocarditis (IE); associated spondylodiskitis has not yet been described in the literature. Purpose We describe 2 patients who presented with new-onset, severe back pain; blood cultures revealed S. gordonii bacteremia, which led to the diagnosis of spondylodiskitis and IE. We review our 2-decade experience with S. gordonii bacteremia to describe the clinical and epidemiological characteristics of these patients. Results In our hospital over the last 20?years (1998–2017), a total of 15 patients with S. gordonii bacteremia were diagnosed, including 11 men and 4 women, and the mean age was 65?±?22 (range 23–95). The most common diagnosis was IE (9 patients), spondylodiskitis (the presented 2 patients, who in addition were diagnosed with endocarditis), necrotizing fasciitis (1), sternitis (1), septic arthritis (1) and pneumonia (1). The 11 patients with IE were treated with penicillin?±?gentamicin, or ceftriaxone for 6?weeks, 5 required valve surgery and 10/11 (91%) attained complete cure. The 2 patients with diskitis required 2–3?months of intravenous antibiotics to achieve complete cure. Conclusion Spondylodiskitis was the presenting symptom of 2/11 (18%) patients with S. gordonii endocarditis. Spondylodiskitis should probably be looked for in patients diagnosed with S. gordonii endocarditis and back pain as duration of antibiotic treatment to achieve complete cure may be considerably longer.
机译:背景戈登链球菌是感染性心内膜炎(IE)的罕见原因。相关的脊椎盘状炎尚未在文献中描述。目的我们描述了2例新发的严重背痛患者。血液培养显示戈登氏链球菌菌血症,导致对脊椎盘状炎和IE的诊断。我们回顾了我们在戈登氏菌中的2年经验,以描述这些患者的临床和流行病学特征。结果在我们医院的最近20年(1998-2017年)中,共诊断出15例戈登氏菌菌血症患者,其中11例男性和4例女性,平均年龄为65?±?22(范围23- 95)。最常见的诊断是IE(9例),脊椎盘状炎(目前有2例,另外被诊断出患有心内膜炎),坏死性筋膜炎(1),胸膜炎(1),化脓性关节炎(1)和肺炎(1)。 11例IE患者接受青霉素?±庆大霉素或头孢曲松治疗6周,其中5例需行瓣膜手术,10/11(91%)完全治愈。 2例椎间盘炎患者需要2-3个月的静脉内抗生素治疗才能完全治愈。结论脊柱椎盘炎是戈氏葡萄球菌心内膜炎的2/11(18%)患者。确诊为戈登氏链球菌性心内膜炎和腰背痛的患者应寻找脊椎盘状炎,因为完成完全治愈的抗生素治疗时间可能会更长。

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