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Amelanotic melanoma masquerading as a superficial small round cell tumor: A diagnostic challenge

机译:伪装成浅表小圆形细胞瘤的黑化性黑素瘤:诊断挑战

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Malignant melanoma poses a remarkable capacity for morphological diversity and often presents as a diagnostic challenge due to its wide clinical presentation. We present a case of a 73-year-old lady, with a large superficial ulcerative nodular mass on the flexor aspect of the right upper arm. On fine needle aspiration poorly differentiated round cell tumor was suggested, with histopathology also supporting the same diagnosis. A final diagnosis of amelanotic melanoma was given following immunohistochemical work-up using a panel of relevant markers. We are presenting this case, not only for its rare clinical presentation, but also for the diagnostic difficulties encountered by us in cytology and histopathology to reach the final diagnosis.
机译:恶性黑色素瘤具有广泛的形态学多样性,并且由于其广泛的临床表现,常作为诊断挑战。本例为一名73岁女士,右上臂屈肌侧有较大的浅表溃疡性结节性肿块。在细针抽吸术中,建议分化低的圆形细胞肿瘤,组织病理学也支持相同的诊断。免疫组化检查后,使用一系列相关标志物对黑素瘤黑色素瘤进行了最终诊断。我们介绍此病例的原因不仅在于其罕见的临床表现,还在于我们在细胞学和组织病理学方面遇到的诊断困难,以达到最终诊断的目的。

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