Prevalence of Vitamin D3 deficiency among patients undergoing angioplasty in a tertiary care centre in Eastern India

摘要

Background: The prevalence of Vitamin D3 deficiency and itsrelationship with clinical parameters in patients undergoing angioplasty,i.e. the higher risk group, in Eastern India is not known.The present study aimed to address this issue.Methods: 241 consecutive patients (212 male and 29 females)undergoing PTCA in a tertiary care centre were enrolled in thestudy. Blood samples for Vitamin D levels were collected alongwith routine pre-catheterization blood samples. Vitamin D levelswere stratified as per Institute of Medicine (IOM) guidelines intonormal (50%.The above data was analyzed with commercially availablestatistical software. Level of significance was assessed with Chisquare test. A p value of <0.05 was considered significant.Results: Of 241 patients 152(63.07%) were deficient, 40(16.59%)were insufficient and 51(21.16%) had normal Vitamin D3 levels.The group with deficiency had highest number of patients withacute coronary syndrome (n?9), ejection fraction <30% (n?4;p<0.05) and triple vessel disease (n?) .We did not find any significantcorrelation between age, gender, lipid levels, presence orabsence of hypertension, diabetes, smoking or alcoholism.Conclusion: In this tertiary care centre of Eastern India majority ofpatients undergoing PTCA had vitamin D3 deficiency. The VitaminD3 deficient group had significant number of patients withEF<30% and showed a tendency towards higher number of ACS(Acute Coronary Syndrome) and triple vessel disease on coronaryangiograms.