Early changes in the hippocampal neurogenesis, neuroinflammation, and behavioral functions following mild traumatic brain injury

摘要

DPG) solvent only) was applied. We found that these fragrances could ameliorate brain responses of severe symptoms toward brain responses of light symptoms. Under no odorant condition, we could observe differ- ent brain response depend on menopausal symptoms severity (KI score) when negative emotion was evoked. The severity of symp- toms showed a significantly negative correlation with alpha power (r=—0.41) and significantly positive correlation with beta/alpha ratio (r= 0.39) which is widely used as an arousal index. These EEG characteristics showed only in psychological symptoms category: depressive symptoms, anxiety, not in physiological symptoms. On the other hands, these significant correlations were disap- peared with fragrance treatments. That is, fragrance treatments sufficiently modulate alpha power and beta/alpha ratio of severe symptoms until vanishing significant correlations.