35 anos da classifica??o de Rezende: a importancia do esofagograma no contexto da doen?a de Chagas no Brasil

摘要

Mr. Editor,Achalasia is a disorder of the lower esophagus in which its sphincter is unable to relax even during a peristaltic reflex. Its development is related to the loss of both Auerbach's (myenteric) and Meissner's (submucous) plexuses of the distal esophagus and lower sphincter, due to a neurodegenerative process that may be autoimmune or secondary to an infection. In Brazil, Chagas disease is one of this disorder's main etiologies, by promoting the destruction of the myenteric plexus due an inflammatory response to the Trypanosoma cruzi. The Chagas megaesophagus is one of its presentations, consisting of the addition of achalasia to ineffective peristalsis that results in esophageal dilatation(1)