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Aspergillus infection in the ascending aorta of a patient with aortic and mitral valve prostheses

机译:主动脉瓣和二尖瓣假体患者升主动脉中的曲霉菌感染

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We report the case of implantation of metallic mitral and aortic valve prostheses 6 months earlier, with subsequent multiple embolic episodes. The anatomicopathological examination of the thrombus of the third embolic episode was compatible with Aspergillus sp, which was treated with amphotericin B, followed by oral itraconazole. On the fourth embolism, vegetations were visualized in the ascending aorta on echocardiography and resonance imaging, and the patient underwent replacement of the aortic segment by a Haemashield tube and exploration of the aortic prosthesis, which was preserved, because no signs of endocarditis were found. Four months later, the patient died due to cardiogenic shock secondary to acute myocardial infarction caused by probable coronary embolism and partial dysfunction of the aortic prosthesis.
机译:我们报告6个月前植入金属二尖瓣和主动脉瓣假体的情况,随后发生多个栓塞事件。第三栓塞发作的血栓的解剖病理学检查与曲霉菌属菌种兼容,后者先用两性霉素B治疗,然后口服伊曲康唑。在第四次栓塞时,通过超声心动图和共振成像观察升主动脉中的植被,并用Haemashield管置换患者的主动脉段并探查保留的主动脉假体,因为未发现心内膜炎的迹象。四个月后,患者死于死于冠状动脉栓塞和部分主动脉假体功能障碍引起的急性心肌梗死继发的心源性休克。

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