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One-stage dorsal lingual mucosal graft urethroplasty for the treatment of failed hypospadias repair

机译:一期背舌舌黏膜移植物尿道成形术治疗尿道下裂修复失败

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The aim of this study was to retrospectively investigate the outcomes of patients who underwent one-stage onlay or inlay urethroplasty using a lingual mucosal graft (LMG) after failed hypospadias repairs. Inclusion criteria included a history of failed hypospadias repair, insufficiency of the local skin that made a reoperation with skin flaps difficult, and necessity of an oral mucosal graft urethroplasty. Patients were excluded if they had undergone a failed hypospadias repair using the foreskin or a multistage repair urethroplasty. Between January 2008 and December 2012, 110 patients with failed hypospadias repairs were treated in our center. Of these patients, 56 underwent a one-stage onlay or inlay urethroplasty using LMG. The median age was 21.8 years (range: 4-45 years). Of the 56 patients, one-stage onlay LMG urethroplasty was performed in 42 patients (group 1), and a modified Snodgrass technique using one-stage inlay LMG urethroplasty was performed in 14 (group 2). The median LMG urethroplasty length was 5.6 ± 1.6 cm (range: 4-13 cm). The mean follow-up was 34.7 months (range: 10-58 months), and complications developed in 12 of 56 patients (21.4%), including urethrocutaneous fistulas in 7 (6 in group 1, 1 in group 2) and neourethral strictures in 5 (4 in group 1, 1 in group 2). The total success rate was 78.6%. Our survey suggests that one-stage onlay or inlay urethroplasty with LMG may be an effective option to treat the patients with less available skin after failed hypospadias repairs; LMG harvesting is easy and safe, irrespective of the patient's age.
机译:本研究的目的是回顾性调查尿道下裂修复失败后使用舌黏膜移植物(LMG)进行一期植入或嵌体尿道成形术的患者的结局。入选标准包括尿道下裂修复失败的历史,局部皮肤不足使皮瓣再手术困难以及需要进行口腔黏膜移植物尿道成形术。如果患者使用包皮或多阶段修复尿道成形术治疗尿道下裂失败,则将其排除在外。在2008年1月至2012年12月期间,我们中心治疗了110例尿道下裂修复失败的患者。在这些患者中,有56名使用LMG进行了一阶段的尿道植入术。中位年龄为21.8岁(范围:4-45岁)。在56例患者中,对42例患者进行了1期嵌体LMG尿道成形术(第1组),对14例患者进行了改良的Snodgrass技术(采用第1期嵌体LMG尿道成形术)(第2组)。 LMG尿道成形术的中位长度为5.6±1.6 cm(范围:4-13 cm)。平均随访34.7个月(范围:10-58个月),在56例患者中有12例(21.4%)发生了并发症,包括7例尿道皮肤瘘(第1组为6例,第2组为1例)和新发尿道狭窄。 5(第1组4个,第2组1个)。总成功率为78.6%。我们的调查表明,在尿道下裂修复失败后,LMG的一期埋置或镶嵌尿道成形术可能是治疗皮肤较少的患者的有效选择。无论患者的年龄如何,LMG的采集都很容易且安全。

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