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Clinical and imaging perspective and unanswered questions in a case of metronidazole induced encephalopathy

机译:甲硝唑诱发脑病的临床和影像学透视以及未解决的问题

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We discuss the clinical and imaging perspective in a case of a 78-year-old male who developed slurring of speech and ataxia acute in onset for the last 3 days. During his hospital stay, he developed multiple episodes of focal seizures without secondary generalization involving the angle of mouth on the right side. The patient had ataxia and positive cerebellar signs. In the past, the patient was treated for amoebic liver abscess and had undergone percutaneous aspiration of abscess. The patient was prescribed oral metronidazole and was discharged. This time, the patient underwent magnetic resonance imaging examination, which revealed lesion highly suggestive of metronidazole-induced encephalopathy. The offending drug was discontinued immediately after which the patient improved clinically. A follow-up scan was performed after 12 days and showed complete resolution of lesions. Key Words: Diffusion-weighted imaging, fluid-attenuated inversion-recovery, metronidazole-induced encephalopathy, magnetic resonance imaging
机译:我们讨论了在一名78岁男性患者的临床和影像学方面的观点,该患者在最近3天内发病时出现言语和共济失调急性发作。在住院期间,他发生了多发性局灶性发作,而没有涉及右侧口角的继发性泛化。该患者有共济失调和小脑体征阳性。过去,该患者接受过阿米巴肝脓肿的治疗,并经皮吸入脓肿。患者经口服甲硝唑口服治疗后出院。这次,患者接受了磁共振成像检查,发现病变高度提示甲硝唑诱发的脑病。违规药物立即停药,此后患者临床状况得到改善。 12天后进行了一次随访扫描,结果显示病变完全消退。关键词:弥散加权成像,液体衰减倒置恢复,甲硝唑诱发脑病,磁共振成像

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